ChromaTan

Whitepapers

Manufactured by Jetting: The Future in Protein A Affinity Matrix Design – a white paper by ChromaTan and Purolite. [PDF]

Integrated Continuous and Single-use (ICS) bio-production platform – a white paper by ChromaTan and Applikon Biotechnology [PDF]

In-Line Turbidity Sensors for Monitoring Process Streams in Continuous Countercurrent Tangential Chromatography – a white paper by ChromaTan and PendoTECH [PDF]

Peer Reviewed Publications

Improved protein A resin for antibody capture in a continuous countercurrent tangential chromatography system – published in Biotechnol Bioeng. 2020 Mar; 117(3); pages 646-653.

Continuous countercurrent tangential chromatography (CCTC) for mixed mode post-capture operations in monoclonal antibody purification - published in Journal of Chromatography A - Volume 1511, pages 37–44, August 2017.

Performance optimization of continuous countercurrent tangential chromatography for antibody capture - published in Biotechnology Progress - Volume 32, Issue 2, pages 430–439, March 2016.

Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography - published in Journal of Biotechnology - Volume 213, Pages 54-64, November 2015.

Continuous Countercurrent Tangential Chromatography for Monoclonal Antibody Purification - published in Separation Science and Technology - Volume 48, Issue 9, pages 1289-1297, May 2013.

Countercurrent tangential chromatography for large-scale protein purification - published in Biotechnology and Bioengineering - Volume 108, Issue 3, pages 582–591, March 2011.

Reducing the Cost of Medicine

With more efficient process development, clinical manufacturing, and commercial manufacturing we aim to help our customers provide the most affordable therapeutics possible to their patients.

Patents

US Patent No. US10324070B2, High efficiency continuous countercurrent tangential negative chromatography, issued on June 18, 2019 (filed on April 22, 2015)
U.S. Patent No. 7,947,175, Continuous Countercurrent Tangential Chromatography System, issued on May 24, 2011 (filed on December 15, 2010)
U.S. Patent No. 7,988,859, Countercurrent Tangential Chromatography Methods, Systems, And Apparatus, issued on August 2, 2011 (filed on March 14, 2009)

Interested in learning more about our protein purification solutions?

Call or email us to learn more about system performance, applications, integration, and case studies.

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